Zvinhu Zvitatu Zvinoita Kuti Ganda Richembere

Chinhu chikuru chinoita kuti ganda richembere:

Mwaranzi yeUV, kutora mifananidzo

70% yekukwegura kweganda kunobva pakugadzira mifananidzo

Mwaranzi yeUV inokanganisa collagen mumuviri wedu, izvo zvinoita kuti ganda rirambe richitaridzika sediki. Kana collagen ikapera, ganda rinenge risisina kusimba, richidzikira, risina kusimba, ganda rinenge risina kuenzana, riine pigmentation yakawanda, ruvara rweganda runobva rwawedzera, uye mamwe matambudziko eganda.

Mwenje wezuva wakakamurwa kuita UVA neUVB. Mwaranzi yeUVB ine marefu marefu uye inogona kungopisa ganda redu chete, isingakwanise kupinda mukati meganda; zvisinei, mwaranzi yeUVA ine marefu marefu uye inogona kupinda nepakati pegirazi yopinda mukati meganda, zvichizopedzisira zvaita kuti collagen isashande zvakanaka uye zvichikonzera kuti pave nemakwinya.

Muchidimbu, UVA inotungamira mukukwegura, UVB inotungamira mukutsva, uye chiedza che ultraviolet chinogona kukanganisa DNA yemasero, kuderedza kushanda kwe fibroblast, uye kugadzirwa kwe collagen kunovharwa, zvichikonzera kushanduka kwemasero, kukwegura, uye apoptosis. Saka, UV iri kwese kwese, kungave kune zuva kana makore, unofanirwa kuita basa rakanaka rekudzivirira zuva.

Chinhu chechipiri chinonyanya kukosha pakukwegura kweganda

Oxidative free radicals

Izwi guru rekuti free radicals ndi'oxygen'. Tinofema oxygen inosvika 98 kusvika 99 muzana pese patinofema; inoshandiswa kupisa chikafu chatinodya uye kuburitsa mamorekuru madiki kuti masero edu agadzike, uye inoburitsa simba rakawanda kuti tsandanyama dzedu dzishande.

Asi pamwe 1% kana 2% yeokisijeni inosarudza nzira yakasiyana uye ine njodzi, huwandu hushoma hweokisijeni, hunowanzonzi mafree radicals, ayo anorwisa masero edu. Nekufamba kwenguva, kukuvara uku kunoungana nekufamba kwenguva.

Zvinonyanya kuoneka zviratidzo zvekukwegura zvinoonekwa paganda. Miviri yedu ine nzira yekudzivirira inogadzirisa kukuvara kunokonzerwa nefree radicals kumasero edu, asi kana free radicals ikaungana nekukurumidza kupfuura zvingagadziriswa nemasero emuviri, ganda rinochembera zvishoma nezvishoma.

Mufananidzo uri pamusoro apa ndiwo chaiwo ganda remuviri wedu, unogona kuona zvakajeka kuti epidermis yepamusoro yakasviba uye dermis yepasi yakajeka zvishoma, dermis ndipo patinogadzira collagen, uye masero anogadzira collagen anonzi fibroblasts, ayo ari michina inogadzira collagen.

Mafibroblast ari pakati pemufananidzo ndiwo mafibroblast, uye dandemutande rakaapoteredza icollagen. Collagen inogadzirwa nefibroblasts, uye ganda diki rine mativi matatu uye rakanyatsobatana, uye mafibroblasts anodhonza zvine simba mafiber ecollagen kuti ganda diki rive nechimiro chakazara uye chakatsetseka.

Uye ganda rekare, fibroblasts uye kubatana kwecollagen pakati pekuputsika kwefibroblasts dzinokura zvinowanzoramba kupinda kwecollagen, nekufamba kwenguva, ganda rakatangawo kukwegura, izvi ndizvo zvatinowanzoti kukwegura kweganda, tingagadzirisa sei oxidation yeganda rakagamuchirwa?

Pamusoro pekunyanya kutarisisa mafuta ekudzivirira ganda, tinogona kushandisa mamwe ane vhitamini A, vhitamini E, ferulic acid, resveratrol nezvimwe zvinoshandiswa muzvigadzirwa zvekuchengetedza ganda; kazhinji tinogonawo kudya michero nemiriwo zvine mavara akajeka, zvakaita sematomatisi, matomatisi akapfuma mu lycopene.

Inogona kupinza okisijeni zvakanaka uye kudzivirira oxidative stress, unogona zvakare kudya broccoli yakawanda, broccoli ine chikamu chinonzi mustard oil glycosides, mushure mekudya chinhu ichi, inochengetwa muganda, kuitira kuti masero eganda akwanise kuzvidzivirira, michero nemiriwo iyi zvinogona kukurudzira masero kuramba kukwegura.

Chinhu chechitatu chinonyanya kukosha pakukwegura kweganda

Kuongororwa kweganda

Glycation, mumashoko ehunyanzvi, inonzi non-enzyme glycosylation reaction kana kuti Melad reaction. Nheyo ndeyekuti kuderedza shuga kunobatana nemapuroteni kana pasina ma enzymes; kuderedza shuga kunodzoserwa zvakanyanya nemapuroteni, uye kuderedza shuga nemapuroteni kunotora nguva yakareba, kuoxidation, uye rearrangement reaction, zvichikonzera kugadzirwa kwezvikamu zvekupedzisira zveglycosylation, kana kuti AGEs muchidimbu.

MaAGE iboka remarara ehupenyu asingadzoreki, eruvara rweyero-brownish, akabatana neasina kutya kuparadzwa kwema enzyme, uye ndeimwe yezvikonzero zvikuru zvekukwegura kwevanhu. Sezvatinokura, maAGE anoungana mumuviri, zvichikonzera kuwedzera kwekuoma kwemadziro emukati metsinga dzeropa, kusawirirana mukugadzirwa kwemapfupa zvichikonzera osteoporosis, uye kuparadzwa kwecollagen ne elastin fibers mu dermis zvichikonzera kukwegura kweganda. Kukwegura kweganda kunokonzerwa ne glycation kunopfupikiswa mumutsara mumwe chete: shuga inoparadza mapuroteni ane hutano uye inoshandura maumbirwo emapuroteni madiki kuita maumbirwo ekare emapuroteni, zvichikonzera kukwegura uye kurasikirwa nekusimba kwe collagen ne elastic fibers mu dermis.