Elastin yemunhu inonyanya kugadzirwa kubva kunonoka embryonic kusvika kunguva yekuzvarwa, uye hapana kana elastin itsva inogadzirwa panguva yekukura. Elastic fibers inopinda shanduko dzakasiyana panguva yekuchembera kwekupedzisira uye photoaging.
1. Gender uye nhengo dzemuviri dzakasiyana
Kare muna 1990, dzimwe nyanzvi dzakaedza vazvipiri 33 kuti dziongorore kutsetseka kweganda mumativi 11 omuviri womunhu.
Inoratidza kuti elasticity yeganda yakasiyana zvakanyanya pakati pezvikamu zvakasiyana; nepo pasina musiyano mukuru pakati pevarume vakasiyana
Ganda elasticity inoderera zvishoma nezvishoma nezera.
2. Zera
Nekukura kwekukura, ganda rekuchembera ganda rinenge rakaderera uye rinochinjika kupfuura ganda diki, uye elastic fiber network inopwanya uye inoderera, ichiratidza seganda flattening uye wrinkles yakanaka; mukukwegura kwekupedzisira, kwete chete fibrous Degradation yeECM components, asiwo kurasikirwa kwezvimwe zvimedu zve oligosaccharide. LTBP-2, LTBP-3, uye LOXL-1 dzose dzaive dzakagadziriswa, uye LTBP-2 neLOXL-1 dzinotamba mabasa anokosha mukudzora nekuchengetedza fibrin deposition, musangano, uye chimiro nekusunga fibulin-5. Kuvhiringidza kwakabatana ne factor expression inobuda senzira dzekuwedzera endo native kuchembera.
3. Zvinhu zvakatipoteredza
Kukuvadzwa kwezvakatipoteredza zvinhu paganda, kunyanya kudhiza, kusvibiswa kwemhepo uye zvimwe zvinhu zvishoma nezvishoma zvakatariswa, asi mhedzisiro yekutsvagisa haina kurongeka.
Photoaging ganda rinoratidzirwa nezvose catabolic uye anabolic remodeling uye shanduko. Ganda rinoita serakagomara uye rakaunyana zvakanyanya nekuda kwete chete nekurasikirwa kwefibrillin-rich microfibrils paepidermis-dermal junction, elastin degeneration, asi zvinonyanya kukosha, pakuiswa kwechaotic elastin zvinhu mukadzika dermis, basa re elastin rinokanganiswa.
Kukuvadzwa kwechimiro kune elastic fiber yeganda hakuchinjiki usati wasvika makore gumi nemasere, uye kuchengetedzwa kweUV kwakakosha panguva yekukura. Panogona kuva nemaitiro maviri e-elastic fiber sunlight: elastic fibers yakasvibiswa ne elastase yakavanzwa nemasero akapoteredza kana kuti irradiated neUV, uye elastic fibers inokotama panguva yekugadzira; fibroblasts ine mhedzisiro yekusimudzira elastic fiber kuchengetedza mutsara. Mhedzisiro yacho inova isina simba, zvichiguma nokukotama.— Yinmou Dong
Iyo shanduko yekuchinja kweganda elasticity inogona kunge isiri pachena zvakakwana kune yakashama ziso, uye isu tinogona kushandisa nyanzviganda diagnostic analyzercherechedza uye kunyange kufanotaura ramangwana kuchinja maitiro ganda.
Semuyenzaniso,ISEMECO or Resur Skin Analyzer, nerubatsiro rwehunyanzvi hwekuvhenekesa uye yakakwirira-tsanangudzo kamera kuverenga ruzivo rweganda, yakasanganiswa neAI yekuongorora algorithm, inogona kuona iyo nhoroondo uye kufanotaura kwekuchinja kweganda.
Nguva yekutumira: Nov-11-2022
