Mushure mekukuvara kwakanyanya kana kusingaperi kune epidermal barriers, iyo inongoerekana yagadzirisa nzira yeganda inomhanyisa kugadzirwa kwekeratinocytes, kupfupisa nguva yekutsiva epidermal masero, uye kuyananisira kugadzirwa nekuburitswa kwema cytokines, zvichikonzera hyperkeratosis uye kuzvimba zvishoma kweganda. . Izvi zvinowanzoitikawo zviratidzo zveganda rakaoma.
Kuzvimba kwenharaunda kunogonawo kuwedzera kuoma kweganda, chaizvoizvo, kuparara kwepidermal barriers kunokurudzira kuumbwa uye kusunungurwa kwezvikamu zvepro-inflammatory cytokines, zvakadai seIL-1he TNF, kuitira kuti phagocytic immune cells, kunyanya neutrophils, iparadzwe. Mushure mekukwezvwa kunzvimbo yakaoma, mushure mokusvika kwaienda, neutrophils secrete leukocyte elastase, cathepsin G, protease 3, uye collagenase muzvikamu zvakapoteredza, uye inoumba uye inopfumisa protease mu keratinocytes. Zvinogona kuitika zvekuwedzera kweprotease basa: 1. Kukuvadzwa kwesero; 2. Kusunungurwa kwepro-inflammatory cytokines; 3. Kukurumidza kupera kwesero-to-sero kushamwaridzana kunokurudzira sero mitosis. Proteolytic enzyme basa muganda rakaoma, iro rinogonawo kukanganisa tsinga dzekunzwa mu epidermis, inosanganiswa ne pruritus uye kurwadziwa. Kushandiswa kwepamusoro-soro kwetranexamic acid uye α1-antitrypsin (protease inhibitor) ku xerosis inoshanda, zvichiratidza kuti xeroderma inobatanidzwa neproteolytic enzyme basa.
Dry epidermis zvinoreva kutichipingamupinyi cheganda chinokanganiswa, lipids inorasika, mapuroteni anoderedzwa, uye zvikonzero zvinopisa zvemunharaunda zvinobudiswa.Kuoma kweganda kunokonzerwa nekukuvara kwechivharoyakasiyana nekuoma kunokonzerwa nekuderedzwa kwe sebum secretion, uye mhedzisiro yepidid supplementation iri nyore kazhinji inokundikana kuzadzisa zvinotarisirwa. Zvizoro zvinonyorovesa zvakagadzirirwa kukuvara kwezvipingamupinyi hazvifanirwe kungowedzera stratum corneum moisturizing zvinhu, senge ceramides, zvakasikwa moisturizing zvinhu, nezvimwewo, asi zvakare funga nezve mhedzisiro ye antioxidant, anti-inflammatory, uye anti-cell division, nekudaro kuderedza kusakwana kusina kukwana. ye keratinocytes. Barrier ganda kuoma kunowanzo kuperekedzwa nepruritus, uye kuwedzera kweantipruritic actives kunofanirwa kutariswa.
Nguva yekutumira: Jun-10-2022
